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H7N3 influenza virus in Canada
An outbreak of a H7N3 influenza virus has been indicated in a rooster barn in Canada. At first, ancillary genetic results indicated the presence of an H7N3 virus in swab and tissue samples taken from the rooster barn. One day later further test results indicate that birds in that barn were exposed to the virus several days prior to the findings as serology titers are demonstrated towards the virus.

H7N3 active infection was further demonstrated with the presence of live virus in tissues from dead birds and swabs.

Initial virus molecular pathotyping indicate that the virus has a high pathogenic molecular pattern.

All samples tested to date from birds located in the other barns on the same premise do not indicate the presence of avian influenza viruses.

Canadian Food Inspection Agency (CFIA) officials continue to proceed with the investigation according to the Notifiable Avian Influenza - Hazard Specific Plan (NAI-HSP).

CFIA will apply restrictions on the movement of poultry and poultry products within 3 kilometres [1.86 miles] of the infected premises.
As an additional safeguard, any poultry operations within 10 kilometres [6.2 miles] of the infected premises will be closely and
regularly monitored for signs of illness.

Source: www.promedmail.org




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SMALL ANIMAL PRACTICE

Toceranib phosphate (Palladia®) in canine gastrointestinal stromal tumorsmembers
Gastrointestinal stromal tumors (GISTs) are uncommon intestinal neoplasms in the dog. Literature regarding adjunctive therapy for GISTs in dogs is sparse. High‐risk GISTs in humans respond to tyrosine kinase inhibition in the adjuvant setting. This recently online published study reviews cases of toceranib phosphate use in dogs with GISTs and provides initial assessment of possible biological activity. A secondary aim was to evaluate patient and tumor characteristics for possible prognostic value.

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