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Feline mucinous cholangiocarcinoma (case report)
A marked peritoneal effusion is not always associated with heart failure or viral diseases like FIP, it can also be due to a rare neoplasia like cholangiocarcinoma. A very interesting case report illustrating the difficulties to get to the diagnosis of this rare neoplasia!

Mucinous cholangiocarcinoma was diagnosed in a 14-year-old, castrated male, domestic shorthaired cat with marked peritoneal effusion. Cytological confirmation of malignancy by fluid analysis and fine-needle, ultrasound-guided aspiration of the liver was followed by histological examination of tissue samples obtained at surgery and necropsy. No observed response followed chemotherapy with doxorubicin and carboplatin. Electron microscopy and immunohistochemistry helped to further characterize this unusual tumor.


Source: Terry M. Jacobs, Paul W. Snyder (2007): Mucinous Cholangiocarcinoma in a Cat. In: Journal of the American Animal Hospital Association 43:168-172 (2007)




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SMALL ANIMAL PRACTICE

Novel intratumoral therapy in canine transmissible venereal tumour
Canine transmissible venereal tumour (CTVT) is a naturally occurring contagious neoplasm of dogs located mainly on the external genitalia of both sexes. The course of vincristine chemotherapy, the most effective and practical therapy, is affected by the immune status of the host. The aim was to investigate recombinant human interferon alpha‐2a (rhIFNα‐2a) and vincristine for treatment of CTVT.

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