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Mycotoxins - dangerous for humans and animals
This excellent study gives an overview over toxicity, metabolism and impact of mycotoxins on both humans and animals. One of the interesting findings: monogatrics are much more susceptible for acute and chronic effects due to mycotoxins than ruminants.

Mycotoxins are secondary metabolites of molds that have adverse effects on humans, animals, and crops that result in illnesses and economic losses.

The worldwide contamination of foods and feeds with mycotoxins is a significant problem. Aflatoxins, ochratoxins, trichothecenes, zearelenone, fumonisins, tremorgenic toxins, and ergot alkaloids are the mycotoxins of greatest agro-economic importance.

Some molds are capable of producing more than one mycotoxin and some mycotoxins are produced by more than one fungal species. Often more than one mycotoxin is found on a contaminated substrate.

Factors influencing the presence of mycotoxins in foods or feeds include environmental conditions related to storage that can be controlled. Other extrinsic factors such as climate or intrinsic factors such as fungal strain specificity, strain variation, and instability of toxigenic properties are more difficult to control.

Mycotoxins have various acute and chronic effects on humans and animals (especially monogastrics) depending on species and susceptibility of an animal within a species. Ruminants have, however, generally been more resistant to the adverse effects of mycotoxins. This is because the rumen microbiota is capable of degrading mycotoxins.

The economic impact of mycotoxins include loss of human and animal life, increased health care and veterinary care costs, reduced livestock production, disposal of contaminated foods and feeds, and investment in research and applications to reduce severity of the mycotoxin problem.

Although efforts have continued internationally to set guidelines to control mycotoxins, practical measures have not been adequately implemented.


Source: Hussein HS, Brasel JM (2001): Toxicity, metabolism, and impact of mycotoxins on humans and animals. In: Toxicology 2001 Oct 15;167(2):101-34




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BOVINE

Monensin and essential oils in transition dairy cows
This work examined preventive effects of a dietary and a medical intervention measure on postpartum (p.p.) ketogenesis in dairy cows overconditioned in late pregnancy. Sixty German Holstein cows were allocated 6 weeks antepartum (a.p.) to three high body condition score (BCS) groups (BCS 3.95 ± 0.08) and one low BCS group (LC, BCS 2.77 ± 0.14). Which effect does the oral addition of monensin and essential oils have on performance parameters and energy status?

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