Home
http://www.virbac.fr/ http://www.boehringer-ingelheim.com/ http://www.novartis.com/ http://www.animalhealth.bayerhealthcare.com/
vetcontact
Vetrinär
Tiermedizin
  WELCOME  
vetcontact
Vetrinär
Tiermedizin
  Home  
  Login / Newsletter  
vetcontact
Vetrinär
Tiermedizin
  CONTACTS  
vetcontact
Vetrinär
Tiermedizin
  Classifieds  
  New Products  
  VetCompanies  
  VetSchools  
vetcontact
Vetrinär
Tiermedizin
  PROFESSION  
vetcontact
Vetrinär
Tiermedizin
  Edutainment  
  VetAgenda  
  Presentations  
  Posters  
  ESAVS  
  Specialisation  
vetcontact
Vetrinär
Tiermedizin
  INSIGHT  
vetcontact
Vetrinär
Tiermedizin
  Congress News  
  Picture Galleries  
vetcontact
Vetrinär
Tiermedizin
  PRODUCTS  
vetcontact
Vetrinär
Tiermedizin
  Bayer  
  Boehringer Ing.  
  Novartis  
  Virbac

 
  Simply book for less...  
    

Bovine    Equine    Small Animal Practice    Swine Practice    Articles    Vetjournal    
deutsch english español polski francais
Home / WELCOME / Archiv / Articles /     
 
Swiss sheep breeds potentially susceptible to scrapie and BSE
Polymorphisms in the prion protein gene (PRNP) gene have both an influence on the progress of scrapie and also of bovine spongiform encephalopathy (BSE) in sheep. In this study form Switzerland, the main Swiss sheep breeds were investigated. The result: All 4 breeds are potentially susceptible to scrapie and BSE!

In the light that sheep are potentially susceptible to BSE the goal of this project was to characterize 50 animals of each of the four major Swiss sheep breeds, namely Swiss Oxford Down, Swiss Black-Brown Mountain, Valais Blacknose and Swiss White Alpine with respect to polymorphisms in the PRNP region.

A 628-bp fragment of exon 3 of PRNP comprising codons 112-211 was amplified by PCR and analysed by direct sequencing.
Heterozygous genotypes were further verified by restriction fragment length polymorphism analyses.

Polymorphisms could be observed at codons 112, 136, 137, 141, 143, 154 and 171 but not at codons 138, 151 and 211. One of the scrapie cases in Switzerland, a sheep of Swiss White Alpine, was also genotyped.

Based on the polymorphisms observed at codons 136, 154 and 171 all four sheep breeds should be considered potentially susceptible to scrapie and BSE.


Source: Gmür, A., Gaillard, C. & Dolf, G. (2004)
Characterization of the prion protein gene (PRNP) region in Swiss sheep breeds. In: Journal of Animal Breeding and Genetics 121 (3), 216-220



Tell a friend   |   Print version   |   Send this article

ARTICLES

Pharmacokinetics of quinocetone in ducks after two routes of administrationmembers
Quinocetone (QCT), an antimicrobial growth promoter, is widely used in food-producing animals. However, information about pharmacokinetics (PK) of QCT in ducks still remains unavailable up to now. In this study, QCT and its major metabolites (1-desoxyquinocetone, di-desoxyquinocetone and 3-methyl-quinoxaline-2-carboxylic) in ducks were studied using a simple and sensitive UHPLC-MS/MS assay.

  • Novel antibiotic treatment of zebrafish mycobacteriosismembers
  • Canine mammary tumours as model for hereditary breast cancer susceptibility genes in humansmembers
  • Treatment of corneal ulceration in stranded California sea lions members
  • Effects of substrates and stress on placental metabolismmembers
  • Vaccine regimens against caecal Salmonella Typhimurium colonisation in laying hensmembers
  • Presumptive keratoglobus in a raptormembers
  • Monitored, controlled long-term anaesthesia in broiler chickenmembers
  • Pharmacokinetics of cefovecin in alpacasmembers
  • Use and effect of hand antiseptics in veterinary practicemembers
  • Two dogs with cold agglutinin activitymembers
  • Mechanical ventilation and blood gases and blood pressure in rattlesnakesmembers
  • Infectious haemolytic anemia in an orphaned juvenile female platypus members


  • [ Home ] [ About ] [ Contact / Request ][ Disclaimer ]

    Copyright © 2001-2016 VetContact GmbH
    All rights reserved