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Lipid profiles in feline hepatic lipidosis
Feline hepatic lipidosis (FHL)is a common and potential life-threatening problem in obese cats which are suddenly anorectic. In this french study, the effects of FHL on some lipid parameters are examined.

This study was designed to determine plasma lipids and lipoprotein profiles in queens at different stages during experimental induction of FHL (lean, obese, FHL), and after 10 weeks of treatment.

Results were compared with those obtained from lean queens of same age fed the same diet but at a maintenance level, once a day.

Hepatic lipidosis led to an increase in plasma triacylglycerol (TG), very low density lipoprotein (VLDL) and low density lipoprotein (LDL), and an enrichment of LDL with TG and of high density lipoprotein (HDL) with cholesterol, suggesting that VLDL secretion is enhanced, VLDL and LDL catabolism is lowered, and lipoprotein exchanges are impaired in FHL.

This study also showed that cholesterolaemia is increased in cats fed at a dietary rhythm of one meal per day compared to ad libitum feeding.

Source: Blanchard, G., Paragon, B. M., Sérougne, C., Férézou, J., Milliat, F. & Lutton, C. (2004): Plasma lipids, lipoprotein composition and profile during induction and treatment of hepatic lipidosis in cats and the metabolic effect of one daily meal in healthy cats. In: Journal of Animal Physiology and Animal Nutrition 88 (3-4), 73-87.




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SMALL ANIMAL PRACTICE

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