Home
http://www.virbac.fr/ http://www.boehringer-ingelheim.com/ http://www.novartis.com/ http://www.animalhealth.bayerhealthcare.com/
vetcontact
Vetrinär
Tiermedizin
  WELCOME  
vetcontact
Vetrinär
Tiermedizin
  Privacy Policy  
  Home  
  Login / Newsletter  
vetcontact
Vetrinär
Tiermedizin
  CONTACTS  
vetcontact
Vetrinär
Tiermedizin
  Classifieds  
  New Products  
  VetCompanies  
  VetSchools  
vetcontact
Vetrinär
Tiermedizin
  PROFESSION  
vetcontact
Vetrinär
Tiermedizin
  Edutainment  
  VetAgenda  
  Presentations  
  Posters  
  ESAVS  
  Specialisation  
vetcontact
Vetrinär
Tiermedizin
  INSIGHT  
vetcontact
Vetrinär
Tiermedizin
  Congress News  
  Picture Galleries  
vetcontact
Vetrinär
Tiermedizin
  PRODUCTS  
vetcontact
Vetrinär
Tiermedizin
  Bayer  
  Boehringer Ing.  
  Novartis  
  Virbac

 
  Simply book for less...  
    

Bovine    Equine    Small Animal Practice    Swine Practice    Articles    Vetjournal    
deutsch english español polski francais
Home / WELCOME / Archiv / Small Animal Practice /     
 
Adaptive radiotherapy techniques for external radiation therapy of canine bladder cancer
Daily bladder variations make it difficult to utilize standard radiotherapy as a primary treatment option for muscle-invasive bladder cancer. The authors´ purpose was to develop a model comparing dose distributions of image-guided and adaptive radiotherapy (ART) techniques for canine bladder cancer.

Images were obtained retrospectively from cone-beam computed tomography (CBCT) scans used for daily positioning of four dogs undergoing fractionated image-guided radiotherapy (IGRT).

Four different treatment plans were modeled for each dog, and dosimetric data were compared.

Two plans were developed using planning target volumes based on planning computed tomography (CT) bladder volume.

These plans then used bony anatomy or soft tissue anatomy for daily positioning and dosimetric modeling.

The third plan type was a hybrid IGRT and ART technique utilizing a library of premade anisotropic planning target volumes using bladder wall motion data and selection of a `plan-of-the-day` determined from positioning CBCT bladder volumes.

The fourth plan was an ART technique that constructed a new planning target volume each day based on daily bladder volume as determined by pretreatment CBCT.

Dose volume histograms were generated for each plan type and dose distribution for the bladder and rectum were compared between plan types.

Irradiated rectal volume decreased and irradiated bladder volume increased as plan conformality increased.

ART provided the greatest rectal sparing, with lowest irradiated rectal volume (P < 0.001), and largest bladder volume receiving 95% of the prescription dose (P < 0.001).

In our model, adaptive radiotherapy techniques for canine bladder cancer showed significant reduction in rectal volume irradiated when compared to nonadaptive techniques, while maintaining appropriate bladder coverage.



Source: Nieset, J. R., Harmon, J. F., Johnson, T. E. and Larue, S. M. (2014), COMPARISON OF ADAPTIVE RADIOTHERAPY TECHNIQUES FOR EXTERNAL RADIATION THERAPY OF CANINE BLADDER CANCER. Veterinary Radiology & Ultrasound, 55: 644–650. doi: 10.1111/vru.12163



Tell a friend   |   Print version   |   Send this article

SMALL ANIMAL PRACTICE

Punica granatum associated with hepatotoxicosis in cattlemembers
The ingestion of pomegranates was associated with the deaths of 9 of 35 young cattle; 8 were found dead without any prior clinical signs being noted and 1 animal was observed to be weak with pale‐pink mucous membranes. This case report describes also gross pathological and histopathological signs of the affected cattle and discusses the question which toxic principle was underlying in this case.

  • Toceranib phosphate (Palladia®) in canine gastrointestinal stromal tumorsmembers
  • Radioactive iodine uptake in hyperthyroid cats after rh-TSHmembers
  • Hypoechoic tissue changes in dogs with malignant prostatic lymphomamembers
  • Emphysematous gastritis in dogs and catsmembers
  • Primary pulmonary histiocytic sarcoma in dogsmembers
  • Determining prognosis in canine sepsis members
  • Correlation of plasma and tear glucose, creatinine and urea nitrogen in catsmembers
  • Perineal hernias in dogs - always a bilateral problem?members
  • Pharmacokinetic of gabapentin in catsmembers
  • Follicular development of canine ovaries stimulated by eCG plus hCGmembers
  • Gastrointestinal effects following acupuncture in healthy dogsmembers
  • Bilateral repair of apparently unilateral perineal hernias in dogsmembers


  • [ Home ] [ About ] [ Contact / Request ] [ Privacy Policy ]

    Copyright © 2001-2018 VetContact GmbH
    All rights reserved