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Secondary hypercalcemia due to iatrogenic Cushing in a cat
Cats are known to have a much higher corticosteroid-tolerance than other species, especially dogs. But it is also possible to cause severe metabolic aberrations with chronic parenteral corticosteroid applications in this species, as this very impressive case report shows.

A 9-year-old, spayed female domestic shorthair cat presented for polyphagia, polydipsia, and polyuria following chronic methylprednisolone acetate therapy for pruritus.

Initial diagnostics were consistent with uncomplicated diabetes mellitus. Serum calcium was within reference range.

Within 12 hours the cat developed depression, anorexia, vomiting, and severe dehydration. Laboratory analysis indicated marked hypercalcemia as measured by both ionized and total calcium concentration. No underlying neoplastic or inflammatory process was identified.

An adrenocorti-cotropic hormone stimulation test was indicative of adrenocortical insufficiency. The hypercalcemia resolved with glucocorticoid supplementation and correction of the dehydration.

The diabetes mellitus and adrenal insufficiency both resolved within 9 weeks.



Source: Stephanie A. Smith, Lisa C. Freeman, Mary Bagladi-Swanson (2002): Hypercalcemia Due to Iatrogenic Secondary Hypoadrenocorticism and Diabetes Mellitus in a Cat. In: Journal of the American Animal Hospital Association 38:41-44 (2002)



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SMALL ANIMAL PRACTICE

Patient-specific facemask to facilitate brain biopsymembers
The objective of this pilot study was to describe the application and first preliminary data of a novel MRI and CT compatible patient-specific facemask for stereotactic brain biopsy of intracranial lesions in dogs. Five client-owned dogs presenting for neurological deficits consistent with forebrain disease were included in the study. All dogs had MRI findings consistent with an intracranial lesion. But biopsies in this region are not easy to obtain. Does an individual face mask help?

  • Critically ill dogs and their immune function
  • RET-He to diagnose iron-deficient erythropoiesis in dogsmembers
  • Hypertriglyceridemia-Associated Proteinuria in Miniature Schnauzersmembers
  • Gastrointestinal dysmotility disorders in critically ill animalsmembers
  • Disorder of sex development in a cat with chromosome mosaicism members
  • Generalized discoid lupus erythematosus in dogs members
  • Epidermolysis bullosa acquisita in dogsmembers
  • Chiari-Like Malformation and Syringomyelia in American Brussels Griffon Dogsmembers
  • Efficacy and Potential Complications of Transjugular Liver Biopsymembers
  • Hypomagnesemia in Brachycephalic Dogsmembers
  • Comparison of two minimally invasive techniques for liver biopsy members
  • Topical aqueous sirolimus and the tear production members


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