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Pulmonary thrombembolism in dogs - a new diagnostic tool
Although the exact incidence of pulmonary thromboembolism (PTE) in small animals is unknown, it is thought that PTE is a substantial, under-diagnosed complication. Clinical signs are sometimes less specific and the diagnosis can become very difficult. the d-dimer might be a good diagnostic tool!

The difficulty in diagnosing PTE in small animals is confounded by its subtle symptomatic presentation and a lack of clinical suspicion, coexisting disease states, and lack of noninvasive tests that are sensitive and specific for the diagnosis of PTE.

Although numerous laboratory markers of coagulation have been studied, only the D-dimer assay has shown clinical utility in detecting early embolism in humans.

This paper in the just published issue of the AAHA jounal examines the use of D-dimer assays and other clinical modalities in the diagnostic approach to thromboembolic disease in small animals.



Source: O. Lynne Nelson (2005): Use of the D-dimer Assay for Diagnosing Thromboembolic Disease in the Dog. In: Journal of the American Animal Hospital Association 41:145-149 (2005)



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SMALL ANIMAL PRACTICE

Bioavailability of suppository acetaminophen in dogsmembers
Does acetaminophen reach a satisfactory biovailability in dogs? An interesting question! This recently published study enrolling healthy and ill animals determines the plasma pharmacokinetics of suppository acetaminophen (APAP). Six healthy client‐owned and 20 clinically ill hospitalized dogs were included in this prospective study.

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  • Characterization of ocular melanosis-affected canine melanocytesmembers
  • Nasopharyngeal sialoceles in brachycephalic dogsmembers
  • Enterococcus faecium SF68 on serum cobalamin and folate concentrationsmembers
  • Gastrointestinal eosinophilic sclerosing fibroplasia limited to the mesentery in a catmembers
  • Ion acid-base disturbances and associated mortality in dogsmembers
  • First description of ultrasonic bone curette in canine otic surgerymembers
  • Staining hair samples with a modified Wright-Giemsa stain to diagnose feline dermatophytosismembers
  • Oral extended release hydrocodone as analgesia after TPLOmembers
  • 25OH vitamin D3 serum concentration in dogs with acute polyradiculoneuritismembers
  • Type 1 immune mediated polyarthritis in dogs and temporal relationship to vaccination members
  • Phosphorus and protein supply before diagnosis of chronic kidney disease members


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