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Carbon monoxide toxicity in dogs and cats
Acute carbon monoxide intoxication has become a rare but still existing emergency. This excellent article summarizes the diagnostics, therapy, and sequelae of acute carbon monoxide (CO) toxicity because of a motor vehicle generator in 4 dogs and 2 cats.

Series summary: Four dogs and 2 cats presented for recumbency, disorientation, dyspnea, and stiffness after an estimated 68 hour exposure to exhaust from a generator.

Diagnostics included a serum carboxyhemoglobin levels evaluation, arterial blood gas analysis, pulse oximetry readings, and blood pressure measurements.

Initial therapy included oxygen (O2) administration, intravenous bronchodilators, fluids, and a hemoglobin-based O2 carrying (HBOC) molecule.

Following administration of the HBOC, 4 of the 6 animals showed dramatic clinical improvement.

Two weeks after hospital discharge, the owner reported potential hearing deficits in all animals.
Brain auditory evoked response (BAER) tests were conducted in all surviving animals and some degree of hearing impairment was documented in all cases, with complete clinical resolution noted 6 weeks later.

A delayed nervous system dysfunction was documented in all surviving animals.


Source: Berent, Allyson C., Todd, Jeffrey, Sergeeff, Jennifer & Powell, Lisa L. (2005): Carbon monoxide toxicity: a case series. In: Journal of Veterinary Emergency and Critical Care 15 (2), 128-135.





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SMALL ANIMAL PRACTICE

Reference intervals for blood parameters in Shetland Sheepdogsmembers
Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs (SSs) are reported to be more predisposed to different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is more often required. Thus, the aim of this study was to determine whether the RIs of the general canine population could be applied to that of SSs, and to generate breed‐specific RIs, where appropriate.

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