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Doramectin against scabies in rabbits
Doramectin, ivermectin and moxidectin are known to be effective against Sarcoptic mange in dogs. Moxidectin was described to be only partial effective in rabbits which is rather surprising. In this study, doramectin is chosen to treat scabies infestation in the very sensitive Angora rabbits. It works!

The efficacy of administering doramectin after moxidectin treatment, which has previously proved only partially effective, was evaluated in five Angora rabbits naturally infested with Sarcoptes scabiei mange.

Evaluations included physical examination for clinical signs of sarcoptic mange and collection of skin scrapings for determination of mites.

The rabbits first received two subcutaneous injections, 10 days apart, of moxidectin 1% injectable solution at a dosage of 0.2 mg kg1 of bodyweight.

Although moxidectin treatment resulted in clinical improvement within 10 days post initial injection, on days 10 and 35 post initial treatment live mites were present in skin scrapings.

Administration of doramectin 1% injectable solution using the same route and dosage and at similar intervals to moxidectin led to complete disappearance of signs of scabies and parasitological cure in all rabbits.


Source: VOYVODA, HUSEYIN, ULUTAS, BULENT, EREN, HASAN, KARAGENC, TULIN & BAYRAMLI, GOKSEL (2005)
Use of doramectin for treatment of sarcoptic mange in five Angora rabbits. In: Veterinary Dermatology 16 (4), 285-288.






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SMALL ANIMAL PRACTICE

Microbiota of traumatic, open fracture wounds and the mechanism of injury
Open fractures are characterized by disruption of the skin and soft tissue, which allows for microbial contamination and colonization. Preventing infection‐related complications of open fractures and other acute wounds remains an evolving challenge due to an incomplete understanding of how microbial colonization and contamination influence healing and outcomes. Culture‐independent molecular methods are now widely used to study human‐associated microbial communities without introducing culture biases. This recently online published study describes the fascinating association between the mechanism of injury and the microbiota of the wounds.

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