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Peritoneal dialysis in dogs with acute renal failure
Peritoneal dialysis is an effective but very time-consuming procedure which is mainly done in veterinary clinics. But it is worth trying it in dogs with acute renal failure: 4 out of 5 dogs with leptospirosis as cause for this problem survived and could be sent back home!

Peritoneal dialysis (PD) was used in the management of 5 dogs with acute renal failure (ARF) caused by leptospirosis.

All dogs were treated for leptospirosis with intravenous (IV) fluids and ampicillin prior to PD.
Median age of dogs was 5 years (range 26 years). All dogs had positive titers for Leptospira bratislava.
Median duration of PD was 4 days (range 316 days).

PD resulted in a decrease in azotemia in all dogs.
Median serum blood urea nitrogen at the start of PD was 192 mg/dL (range 140235 mg/dL) and at the end of PD was 63 mg/dL (range 48139 mg/dL). Median serum creatinine at the start of PD and the end was 12.8 mg/dL (range 7.716.9 mg/dL) and 3.4 mg/dL (range 1.411.1 mg/dL), respectively.

Complications identified during PD included hypokalemia (n=3, 60%), hypoalbuminemia (n=2, 40%), hypomagnesemia (n=1, 20%), pelvic limb edema (n=2, 40%), central nervous system signs (n=2, 40%), dialysate retention (n=1, 20%), and leakage from the catheter site (n=1, 20%).

Peritonitis was not identified in any of the dogs.

Four dogs (80%) survived to discharge from the hospital. PD was effective for management of uremia in dogs with ARF caused by leptospirosis.


Source: Beckel, Nicole F., O`Toole, Therese E., Rozanski, Elizabeth A. & Labato, Mary A. (2005):
Peritoneal dialysis in the management of acute renal failure in 5 dogs with leptospirosis. In:
Journal of Veterinary Emergency and Critical Care 15 (3), 201-205.





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