ASSOCIATION BETWEEN GENOME AND AGGRESSION IN GROUP-HOUSED PIGS
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Aggression in groupâhoused pigs is a welfare concern and can negatively affect production. Skin lesions are reliable indicators of aggression and are moderately heritable, suggesting that selective breeding may reduce aggression. To further understand the genetic control of behavioral traits, such as the aggressive response to regrouping, associated single nucleotide polymorphisms (SNPs) can be identified within the genome, and the region in which these SNPs are located can be related to known genes. A fascinating approach to this problem!
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To investigate SNPs associated with aggression, 1093 purebred Yorkshire pigs were strategically remixed into new groups of familiar and unfamiliar animals at three life stages and lesion counts were recorded.
Genomic best linear unbiased prediction (GBLUP) models were fitted for each trait.
The genetic additive effect was obtained from a genetic relationship matrix constructed from the 50 924 SNPs.
SNP effects and their variances were estimated from the GBLUP objects.
SNPs that were associated with a significant portion of the trait variance were identified for lesions to the anterior (three SNPs, FDR <5%) and central (one SNP, FDR <5%) portions of the body in growâfinish pigs.
These SNPs were located on chromosome 11, suggesting that chromosome 11 contains a region explaining variation in lesion counts that should be further explored to identify genes underlying biological control of aggression.
Source: K. E. Wurtz J. M. Siegford C. W. Ernst N. E. Raney R. O. Bates J. P. Steibel, Genomeâwide association analyses of lesion counts in groupâhoused pigs. AGE, Early View. First published: 22 August 2018 https://doi.org/10.1111/age.12713
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