Seventy-eight healthy adult Dogs were enrolled.
The ONSD was measured by a standardized transpalpebral approach.
Regression analysis showed the relationship between weight and ONSD was better fit with a linear model (R2 = 0.8510) than an allometric model (R2 = 0.7917).
Multiple regression analysis showed ONSD is associated with weight (P < 0.0001), age (P = 0.0021), and BCS (P = 0.0007), but not with sex.
Dominance analysis showed 94.6% of the variance explained by the model was due to weight. Intraclass correlation coefficient (ICC) analysis showed excellent interobserver (ICC = 0.9338–0.9608) and intraobserver (ICC = 0.9893) reliability.
These results suggest that ONSD-US may be reliably measured in dogs using our described transpalpebral approach, and we have calculated prediction intervals based on body weight.
Future studies are needed to determine if ONSD-US measurements are associated with intracranial hypertension as shown in human medicine.
Source: Smith, J. J., Fletcher, D. J., Cooley, S. D. and Thompson, M. S. (2017), Transpalpebral ultrasonographic measurement of the optic nerve sheath diameter in healthy dogs. Journal of Veterinary Emergency and Critical Care. doi:Â 10.1111/vec.12677
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