The ulcer was initially nonresponsive to medical therapy, but showed rapid and appropriate healing following diamond burr debridement.
Proliferative conjunctivitis markedly improved following topical antiviral therapy with cidofovir 1%, interferon alpha 2B ophthalmic solutions, and oral lâ€lysine.
Histopathologic evaluation of a conjunctival biopsy revealed epithelial features suspicious for viral cytopathic changes and intranuclear structures suspicious for viral inclusions, suggestive of a possible viralâ€induced papillomatous conjunctivitis.
A novel alphaherpesvirus, referred to as Strigid Herpesvirus 1 (StrHV1), was identified using PCR and gene sequencing.
This case represents a new clinical manifestation of a previously unreported herpesvirus in the GHOW.
Identification of the herpes virus was critical to administration of appropriate therapy and resolution of the conjunctivitis, and corneal epithelial debridement promoted resolution of the chronic corneal epithelial defect.
Source: Molly D. Gleeson Bret A. Moore Sydney G. Edwards et al, A novel herpesvirus associated with chronic superficial keratitis and proliferative conjunctivitis in a great horned owl (Bubo virginianus). Veterinary Ophthalmology, Early View.irst published: 14 April 2018 https://doi.org/10.1111/vop.12570
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